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Khondrion is a clinical-stage pharmaceutical company discovering and developing therapies targeting mitochondrial disease.

 

khondrion

Khondrion is a clinical-stage pharmaceutical company discovering and developing therapies targeting mitochondrial disease. Founded by Professor Jan Smeitink, a world-leader in mitochondrial medicine, the company is advancing its proprietary science through a wholly-owned clinical and preclinical small molecule pipeline of potential medicines.

for patients & families

To accelerate the discovery and development of its potential medicines for mitochondrial diseases, we work closely with patients and their families, and a network of patient organisations internationally, to ensure our research programmes are always focused on the needs of patients.

“The solution is within our reach”

Since 2012 Khondrion has been progressing a pipeline with the potential to deliver transformative medicines for patients living with mitochondrial disease.

R&D

partnering

At Khondrion, we know that working in collaboration with others is important to accelerate the development of innovative new medicines. That is why we are pursuing the newest science both within our own labs and through partnerships across an extensive clinical and academic network, exploring new avenues of science and sharing knowledge of mitochondrial disease to help develop important new treatments for patients.

Reflections on SSIEM annual symposium 2019 – Building Bridges

Reflections on SSIEM annual symposium 2019 – Building Bridges   Chief Executive Officer of Khondrion, Prof....

Khondrion granted Orphan Drug Designation for KH176 for the treatment of MIDD from European Commission

Khondrion granted Orphan Drug Designation for KH176 for the treatment of maternally inherited diabetes and deafness...

BIO-Europe 2018: Interview with Mike Ward, Chief Content Officer at Informa Pharma Insights

In November 2018, Jan Smeitink, founder and CEO of Khondrion attended the 24th Annual BIO-Europe conference in...

New Year brings new look at khondrion.com

Khondrion, the clinical-stage pharmaceutical company discovering and developing therapies targeting mitochondrial...

Scientific publication in Cell Death & Disease

Results from collaborative preclinical research effort investigating Leigh disease patient cells published in Cell...

Jan Smeitink interview with Catalyze

In July 2018 Khondrion was awarded €2.3M funding from the EU Horizon 2020 Research and Innovation programme to progress clinical development of KH176, its lead pipeline asset. Prof. Dr. Jan Smeitink, Chief Executive Officer of Khondrion, talks to Catalyze®, who collaborated with Khondrion on the company’s successful funding submission, about his ambitions for Khondrion and the mitochondrial disease research his team is leading.

Publication of the KHENERGY study results

KHENERGY study provides first data on safety and efficacy of KH176 in patients with mitochondrial disease. Results from phase IIa study of innovative reduction-oxidation modulator published in Clinical Pharmacology and Therapeutics.

Khondrion awarded H2020 SME Instrument grant

Khondrion receives €2.3M funding from EU Horizon 2020 SME instrument phase 2 program.

KH176 published in Scientific Reports

Khondrion, a leading clinical-stage pharmaceutical company focusing on small molecule therapeutics for mitochondrial diseases, today announced the publication of a scientific article reporting on the development and unique mode of action of KH176, a clinical-stage drug candidate for the treatment of mitochondrial diseases.

Khondrion presents Phase II KHENERGY trial data

Khondrion presents Phase II KHENERGY trial data. Data supporting Phase III development of KH176 in mitochondrial disease.

get in touch

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